Wrinkle reduction
with botulinum toxin

Botulinum toxin treatment is the most popular cosmetic procedure to reduce wrinkles between eyebrows and on the forehead, and to remove fan-shaped wrinkles around eyes.

The most frequent question is how long does the effect of botulinum toxin last. Based on our long experience, we can say the length of the effect varies with each individual and depends mainly on the dose size. The effect usually starts 3-7 days after the application and lasts about 3-6 months. After repeated applications, the effect may sometimes be longer.

However, even botulinum toxin may have some drawbacks. In some clients, the body produces an antidote against botulinum toxin after repeated applications. It may completely eliminate the effect of the next application. Long-term observations have revealed, that this process occurs more often in high doses over 300 units per one application or in repeated applications in a shorter period less than one month. However, we recommend neither such frequency of repetitions nor volumes over 300 units.

What is botulinum toxin?

The effective substance is called botulinum toxin type A which reduces muscle tension. Small doses are applied to selected facial mimic muscles to eliminate their function temporarily. It results in a reduction of mimic wrinkles in the face. The treated muscle resumes its function after some time.

Botulinum toxin has a similar effect on sweat glands, which is used to reduce sweating. Do not be afraid. Botulinum toxin is safe.

It is usually applied in doses ca 25 units per one session.

About botulinum toxin treatment

  • The treatment with botulinum toxin embodies many advantages. 
  • The treatment with botulinum toxin is quick, almost painless and does not limit you in subsequent activities for a long time.
  • Another advantage is, paradoxically, the temporary effect of botulinum toxin. When the effect vanishes, you can freely decide if you want to repeat the procedure or choose another wrinkle reduction or facial rejuvenation method.
Proven Method
Immediate effect

Are you considering botulinum toxin treatment and need advice?

Consult our experienced professionals on-line.

Surgical process

  1. No special preparation is necessary before the application of botulinum toxin; the whole outpatient procedure takes about 10 minutes.
  2. You should inform your surgeon if you take any anticoagulants (Warfarin, Pelentan, Ticlid, Anopyrin etc.)


Do not massage or treat in any way the treated area for at least 6 hours. Do not lie down for circa the same period.

To maximize the effect, try to use the mimics in the treated area as much as possible for at least 2-3 hours.

Avoid physical activities, saunas, sunbeds and spaces with changing pressures for 2-3 days. Do not undergo any beauty treatments earlier than in 2 weeks.


Our team includes solely certified plastic surgeons with broad experience. Their highly professional and yet empathetic approach is our biggest benefit.

Possible risks of the procedure

From time to time, a local reaction after the puncture to the subcutaneous layer may occur, including swelling, small bruises, pain, reddening. Temporarily, a headache or fatigue may occur. These symptoms, if they occur, are moderate and disappear within several hours.

Another complication may be an undesired effect - weakening of muscles in a different place or in a different scope than required. However, this effect is only temporary and disappears within several months.

Botulinum toxin must not be applied in an inflamed area. Although no teratogenous or other negative effects have been reported in women who underwent botulinum toxin treatment in gravidity, botulinum toxin is not applied in these cases and we recommend waiting until you give birth and stop breast feeding.

We do not recommend botulinum toxin treatments if you suffer from diseases with insufficient transmission of nerve impulses - myasthenia gravis (a disease causing weakness in the skeletal muscles). Further, the application is not recommended if you take some medications: aminoglycosides (antibiotics Gentamycin and Streptomycin), Penicillamine, Quinine, calcium channel blockers (medications to decrease blood pressure).

Your surgeon will discuss the risks and limitations with you before the procedure.

Why choose us?

A top team of plastic surgeons

Our team consists of the best certified professionals. We have valuable experience and excellent references.

Thousands of successful procedures

Our surgeons have been in the business for more than 20 years. They have successfully performed thousands of operations and helped many patients.

State-of-the-art operating theatre

Our equipment and applied standards meet the strictest international standards. It is important for a successful surgery as well as for your safety after the procedure.

Do you consider a treatment?

What are the most frequent questions? You can ask us about anything. Don't feel ashamed, we are ready to help you.

Plan an appointment today. An experienced doctor will take care of you and you will learn many important facts.

Do you need advice? Contact us right now, we are at your disposal. We are ready to help you by formulating a question or scheduling an appointment with our doctors.

Plan an appointment

An experienced doctor will take care of you and you will learn many important facts.


+420 549 213 660

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